Dolutegravir Tablets 50 mg – XAPAVIR Tablet

Xapavir 50 mg is an antiretroviral medication used in the management and treatment of HIV-1 infection. This medication contains Dolutegravir as its active ingredient, which belongs to the class of integrase strand transfer inhibitors (INSTIs). Xapavir 50 mg is designed to reduce the viral load in the body, thereby helping to preserve and strengthen the immune system.

How Xapavir 50 mg Works

Xapavir 50 mg utilizes the potent action of Dolutegravir to combat HIV:

• Dolutegravir (50 mg): As an INSTI, Dolutegravir inhibits the HIV integrase enzyme, which is essential for the viral replication process. By blocking this enzyme, Dolutegravir prevents the integration of viral DNA into the host cell’s genome, effectively halting the replication of the virus.

Indications and Usage

Xapavir 50 mg is prescribed for:

• Treatment of HIV-1 Infection: Used in combination with other antiretroviral agents for individuals who have not previously received treatment for HIV-1.
• Maintenance Therapy: For patients who have achieved viral suppression with a stable antiretroviral regimen.

Note: Xapavir 50 mg is not a cure for HIV/AIDS. It should be used as part of a comprehensive treatment plan that includes regular medical monitoring and strict adherence to prescribed therapies.

Dosage and Administration

• Recommended Dose: Take one tablet of Xapavir 50 mg once daily, with or without food.
• Administration Tips:
  • Swallow the tablet whole with a glass of water.
  • Maintain a consistent dosing schedule to maximize effectiveness.
  • Do not alter the dose or discontinue use without consulting your healthcare provider.

Possible Side Effects

Like all medications, Xapavir 50 mg may cause side effects. Common side effects include:

• Nausea
• Headache
• Diarrhea
• Fatigue
• Insomnia

Serious Side Effects (seek medical attention immediately if you experience):

• Severe Allergic Reactions: Rash, itching, swelling, severe dizziness, trouble breathing.
• Liver Problems: Yellowing of the skin or eyes, dark urine, persistent nausea or vomiting.
• Mood Changes: Depression, anxiety, or unusual mood swings.
• Bone Density Loss: Increased risk of fractures or osteoporosis.

Precautions and Warnings

Before taking Xapavir 50 mg, inform your healthcare provider if you:

• Have a history of liver or kidney disease.
• Are pregnant, planning to become pregnant, or breastfeeding.
• Are taking other medications, including over-the-counter drugs and supplements, to avoid potential interactions.
• Have a history of lactic acidosis or severe liver problems.
• Have osteoporosis or are at risk for bone density loss.

Important: Do not take Xapavir 50 mg if you are allergic to Dolutegravir or any other component of the medication.

Drug Interactions

Xapavir 50 mg may interact with other medications, which can affect how Xapavir 50 mg or the other drugs work. Inform your healthcare provider about all the medications you are taking, including:

• Antacids and Supplements: Can affect the absorption of Dolutegravir.
• Certain Antibiotics and Antifungals: May require dosage adjustments.
• Other Antiretrovirals: Potential for increased side effects or reduced efficacy.
• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Increased risk of kidney problems.

Storage Instructions

• Keep Xapavir 50 mg in its original packaging, tightly closed.
• Store at room temperature between 20°C to 25°C (68°F to 77°F).
• Protect from Moisture and Heat: Do not store in the bathroom or other humid areas.
• Keep Out of Reach of Children.