LENVAKAST-4 – Lenvatinib Capsules 4 mg

LENVAKAST- Lenvatinib 4 mg Capsules – www.galaxysuperspeciality.com

LENVAKAST is a medication which contains the active substance called lenvatinib. This medication is used on its own for treating progressive or advanced type of thyroid cancer in adults when radioactive iodine treatment has failed to help in stopping the disease.

LENVAKAST can also be used on its own for treating hepatocellular carcinoma (liver cancer) amongst adults who have not been treated before with another anticancer medicine that travels through the bloodstream. People are prescribed LENVIMA when their liver cancer spreads or cannot be removed through surgery. (Enquiry now online at Galaxysuperspeciality at affordable prices). Lenvatinib 10mg (LENVIMA) Capsules are a prescription anticancer medicine that is manufactured by Eisai Manufacturing Limited. It functions by interfering with the growth and spread of cancer cells in the body.

Indication for use of LENVAKAST: www.galaxysuperspeciality.com

LENVAKAST functions by blocking the action of a type of proteins referred to as receptor tyrosine kinases (RTKs), which are involved in developing of the new blood vessels that supply oxygen and nutrients to the cells which help them grow. These proteins can be found in high amounts within the cancer cells and LENVIMA blocks their action by slowing the rate at which the cancer cells can multiply and also slowing the growth of the tumour, it also helps to cut off the blood supply which the cancer needs to grow further. You can enquire Lenvatinib online from Galaxysuperspeciality that provides genuine medicines with direct shipment from the manufacturer. They have obtained contracts directly on the manufacturer’s website for countries like USA, Peru, Romania, China and Russia or in the country of its production.

Note: Lenvatinib 4 mg (LENVAKAST) Capsules are only available with a prescription.

Composition of Lenvatinib 4 mg: www.galaxysuperspeciality.com

LENVAKAST contains the active substance called lenvatinib.
Each hard capsule of LENVAKAST 4 mg contains 10 mg of lenvatinib, as mesilate.

The other ingredients in LENVAKAST are: www.galaxysuperspeciality.com

Calcium Carbonate
Mannitol
Microcrystalline Cellulose
Hydroxypropyl Cellulose
Low- substituted Hydroxypropyl Cellulose
Talc

The capsule shell of LENVAKAST contains:

Hypromellose
Titanium Dioxide (E171)
Yellow Iron Oxide (E172)
Red Iron Oxide (E172)

The printing ink on the capsule shell of LENVAKAST contains:

Shellac
Black Iron Oxide (E172)
Potassium Hydroxide
Propylene Glycol

Precautions for Lenvatinib 4 mg:www.galaxysuperspeciality.com

Do not consume LENVAKAST if you have or have had the following conditions:

You are allergic to lenvatinib or any other contents of the medication mentioned above.
You are lactating.

Inform your doctor of the following before starting LENVAKAST:

High Blood Pressure
If you are planning to get pregnant.
Have a history of heart issues or have experienced a stroke
Have or had liver/ kidney problems.
Have had a surgery or radiotherapy recently
Will be getting a surgical procedure done soon. In this case the doctor may need to consider stopping LENVAKAST, as it may hinder the healing process of your body. The medication may be started after a suitable amount of healing has been done.
If you are above 75 years of age.
If you belong to any ethnic group other than White or Asian.
If you weigh less than 60 kg.
If you have a history of fistula (abnormal connections) between different organs in the body or from organ to the skin

Before prescribing LENVAKAST your doctor will carry out some tests to determine the potency of the medicine and will discuss the results with you. If your condition advises then you may need to get additional treatment with other medicines and take a lower dose of LENVAKAST, or you may also be advised to take extra care due to an increased risk of side effects.

Contradictions of Lenvatinib 4 mg:

In children and adolescents

LENVAKAST is not a recommended medication for the use in children and adolescents as the results of this medication among people younger than 18 years are not known.

Usage of LENVAKAST with other medications

There could be some interactions with the drugs that you might be taking or have taken in the past (including herbal medications), therefore, it is necessary to inform your doctor before you start consuming LENVAKAST.

Contraception, Pregnancy and Lactation

Take your doctor’s advice before starting with LENVIMA if you are:

–          Pregnant

–          Lactating/ Breast- feeding

–          Think you might be pregnant

–          Planning to get pregnant

Do not consume LENVAKAST if you are planning to become pregnant as it may seriously harm the baby. If you get pregnant during the treatment, inform your doctor immediately. Your doctor will modify the course of treatment based on your condition. Do not breast feed while on LENVAKAST as the medicine may pass into the breast milk and lead to serious harm to the breastfed baby.

Note: If there is a chance of conceiving, prefer to use a highly effective contraceptive measure while on this medication and for at least a month after the treatment has finished. As LENVAKAST is known to reduce the effect of oral contraceptive pill- if this is the regular contraception method used by you, ensure to also add another barrier such as a condom or cap.

Driving and using other machines

It is advised to avoid driving or using machines as LENVAKAST may cause side effects such as feeling dizzy or tired, which may hinder your ability to drive or use other machines.

Instructions for the Use of Lenvatinib 4 mg:

For Thyroid cancer:

The recommended dose of LENVIMA most commonly prescribed is 24 mg once a day (2 capsules of 10 mg and 1 capsule of 4 mg).
If the condition is severe such as the patient has liver or kidney problems, the recommended dose is changed to14 mg once a day (1 capsule of 10 mg and 1 capsule of 4 mg).

The doctor may reduce your dose if you experience major side effects.

How to consume this medicine:

The capsules can be taken with or without food.
Swallow the capsule as a whole with water or in a dissolved form. (For dissolving them, add a tablespoon of water or apple juice in a glass and add the capsule in it, without breaking or crushing it. Leave it for at least 10 minutes then stir for a minimum of 3 minutes till the capsule dissolves completely. Drink the mixture and after drinking pour same amount of water or apple juice, swirl and drink it.
Take the capsules at the same time each day.
Do not open the capsule as interactions with the powder can be harmful.

For how long should you take LENVIMA?

Take the medicine only for as long as you are prescribed to consume it, taking it for a prolonged period of time can have harmful effects.

What should you do in case you forget to take LENVIMA?

Do not take a double dose the same day to compensate for the forgotten dose.

If there are 12 hours remaining for your next scheduled dose, take the dose as soon as you remember and from the next day onwards take the dose as per your normal routine.

If the remaining time is less than 12 hours until your next dose, skip the missed dose and from the next day onwards take the dose as per your normal routine.

Note: Always consume LENVAKAST exactly as your doctor has prescribed.

Side Effects of LENVAKAST :

Inform your doctor immediately if, you notice any of the below mentioned side effects:

–          The following can be signs of a stroke, bleeding in brain, or the effect of a severe increase in blood pressure in the brain:

Feeling numb or weak on one side of your body
Severe headache
Seizure
Confusion
Difficulty talking
Vision changes or feeling dizzy

–          The following may be signs of a heart problem, a blood clot in your lung or a leak of air from your lung into your chest causing a lack of inflation in your lung:

Chest pain or feeling of pressure
Pain in arms, back, neck or jaw
Shortness of breath
Rapid/ irregular heart rate
Severe and continuous coughing
Bluish colour on lips or finger
Fatigue

–          The following symptom may be because of a hole in the wall of your gut or fistula (a hole in your gut that links through a tube- like passage to another part of the body or skin):

severe pain in the abdomen/ belly

–          The following symptom may be sign of bleeding inside the body:

Black, tarry, or bloody stools
Coughing up blood

–          The following may be signs of liver problems:

Yellow skin or yellowing of sclera (the white part in the eye)
Drowsiness
Confusion
Poor concentration

Most Common Side effects that can cause serious kidney failure if become dehydrated and if they are not taken care of:

Diarrhoea
Feeling and being sick for long

Consult your doctor for a suitable treatment for the above mentioned symptoms.

Other side effects include:

The following side effects are very common that may affect more than 1 in 10 people:

High/ low blood pressure
Weight loss/ loss of appetite
Feeling sick and staying sick for long
Constipation
Diarrhoea
Abdominal pain
Indigestion
Feeling fatigued/ weak
Hoarse voice
Swelling in the legs
Rashes
Dry/ sore/ inflamed mouth
Odd taste sensation
Joint/ muscle pain
Feeling dizzy
Hair loss
Bleeding (nose bleeds are most common but there are other types of bleeding also like blood in urine, bruising, bleeding from gums or gut wall)
Sleeping troubles
Increased protein in urinary tests and increased frequency of urinary infections in urination with pain in passing urine
Headache
Back pain
Redness, soreness and swelling on the skin of hands and feet
Underactive thyroid
Low potassium levels and calcium levels
Decreased white blood cells
Impaired liver functioning
low levels of platelets in the blood that may result in bruising and difficulty in healing of wounds

The following side effects are common that may affect up to 1 in 10 people:

Dehydration
Heart palpitations
Dry, thickening and itching of the skin
Feeling of bloating or excessive wind in the body
Heart problems
Blood clots in the lungs (leading to difficulty in breathing, chest pain) or other organs
Liver failure
Drowsiness
Confusion, poor concentration or loss of consciousness that may be signs of liver failure
Inflammation of the gallbladder
Stroke
Anal fistula (a small channel that gets formed between the anus and the surrounding skin)
Low magnesium levels
High cholesterol levels
High thyroid stimulating hormone
changes in blood reports for kidney function and kidney failure
Increase in lipase and amylase (enzymes that are involved in digestion)

The following side effects are uncommon that may affect up to 1 in 100 people:

Painful infection or irritation near the anus
Chances of getting a mini- stroke
Liver damage
Severe pain in the upper left part of the belly (abdomen) that may be linked with fever, chills, nausea and vomiting (also called splenic farction)
Inflammation of the pancreas
Delayed wound healing
Severe pain in back, chest or abdomen that may be linked with tearing in the wall of the aorta and internal bleeding

How to store Lenvatinib 4 mg?

Keep LENVAKAST out of reach and sight from children
Do not use the medicine after the date of expiry that is stated on the carton and each blister of the medicine.
Do not store the medicine above 25°C.
Store in the original blister in order to protect moisture.
Do not throw away any medicines as water- waste or through household waste. Ask your pharmacist how to dispose of the medicines you no longer need (following this measure will help protect the environment and people around us).