Duovir – Lamivudine and Zidovudine Tablets IP

Description

what is Duovir used for?

Duovir tablets are {a blend|a combo} treatment for {Human being|Individual|Man} Immunodeficiency Virus (HIV) {contamination|illness|disease} in patients with or without acquired immunodeficiency {symptoms|problem|affliction} or AIDS. HIV affects the immune system by attacking specific immune {cellular material|skin cells} called CD4 cells that are involved in {preventing|struggling|struggling with} infection which can lead to opportunistic life-threatening {contamination|illness|disease} (infections that would not normally be harmful). Duovir tablets help prevent or slow down the {capability|capacity|potential} of HIV to {reproduce|duplicate|repeat}, which keeps the amount virus {right down to|into|to} a low level and this {leads to|brings about|ends in} an increase in CD4 cell numbers, so that the immune system can recover reducing the risk of disease progression.

Just how does Duovir work?

Duovir tablets contain {a blend|a combo} of two antiretroviral drugs lamivudine and zidovudine, which both belong to class of drugs known as nucleoside analogue reverse transcriptase blockers (NRTI) that are only effective against retroviruses (RNA virus) like HIV. A nucleoside is a building block of DNA that is needed by the virus to replicate, and nucleoside analogues, like lamivudine and zidovudine in Duovir tablets, become incorporated into the DNA that is copied from the {computer virus|disease|malware} RNA by an chemical called reverse transcriptase. This kind of blocks the action of reverse transcriptase and ends the viral DNA {string|cycle|sequence} so that it {are not able to|are unable to|simply cannot} become integrated into the DNA of the {contaminated|afflicted} immune cell, which means that no more HIV can be produced. Lamivudine is highly synergistic with zidovudine, which means that it increases the {performance|efficiency|success} of zidovudine so that the {blend|combo} of these two antiretroviral drugs in Duovir tablets slow up the replication of HIV {in the body|in the human body} but cannot prevent the spread of the infection to others.

{Exactly what does|How much does} Duovir contain?

Duovir tablets contain {a blend|a combo} the {elements|substances|materials} lamivudine (150mg) and zidovudine (300mg), which are antiretroviral drugs that {are being used} to treat HIV infection.
Dealing with HIV infection with Duovir

Duovir tablets contain {a blend|a combo} of two antiretroviral drugs lamivudine and zidovudine which {are being used} {to deal with|to take care of} HIV {contamination|illness|disease} in patients with or without acquired immunodeficiency {symptoms|problem|affliction} or AIDS. HIV affects the immune system by attacking specific immune {cellular material|skin cells} called CD4 cells that are involved in {preventing|struggling|struggling with} infection which can lead to opportunistic life-threatening {contamination|illness|disease} (infections that would not normally be harmful). Lamivudine and zidovudine in Duovir tablets are inhibitors of the enzyme reverse transcriptase which is needed by retroviruses (RNA viruses) like HIV {to be|to get|for being} incorporated into the DNA of {contaminated|afflicted} immune cells {to enable them to|in order to} {reproduce|duplicate|repeat}. Duovir tablets {assist in preventing|prevent} or slow down the {capability|capacity|potential} of HIV to {reproduce|duplicate|repeat}, which will keep the amount virus down to {a minimal|a decreased} level and this results in {a surge|a climb|a go up} in CD4 cell {figures|amounts|quantities}, {so the|in order that the} immune system can recover, reducing the risk of disease progression.
{Exactly what are|Precisely what are|Exactly what} the side effects of Duovir?

One of the most commonly reported {part|aspect|area} effects when taking Duovir include: headache, gastrointestinal {annoyed|disappointed|cantankerous}, particularly nausea, also diarrhoea, constipation, stomach pain; {fatigue|feeling giddy}, fatigue, difficulty sleeping, {allergy|break outs}, {baldness|hair thinning|hairloss}, muscle and {bones|joint parts|articulations} {pains and aches|discomfort}. A more serious but less common {part|aspect|area} effect is {harm to|problems for|injury to} the liver and {a disorder|an ailment|a problem} called lactic acidosis, {which might|which can|that might} cause pancreatitis, liver failure, or renal failure.
When should Duovir not {be applied|be taken|provide}?

You should not use Duovir if you:
are {sensitive|hypersensitive|sensitized} to lamivudine or zidovudine or any type of ingredients in Duovir tablets
are pregnant or are breastfeeding, without discussion with {your physician|your medical professional|a medical expert}
have abnormally low neutrophil counts ( <0. 75 x 109/l), or abnormally low haemoglobin levels ( <7. 5 g/dl or 4. 65 mmol/l)
{have experienced|experienced|have gotten} any blood disorders such as anaemia or bone marrow problems
have kidney or liver disease
are taking medicines that interact with Duovir, including: the antibiotic trimethoprim, the antriretrovirals zalicitabine and stavudine, the antiinfective atovaquone, the anticonvulsant phenytoin, probenecid for gout, the antivirals ribavirin and ganciclovir, the antiseptic rifampicin, the narcotic {pain reducers|pain killers} codeine and morphine, methadone for treatment of narcotic withdrawal, the non-steroidal antiinflammatoires (NSAID) aspirin, indomethacin, ketoprofen and naproxen, oxazepam and lorazepam for anxiety and sleeping problems, cimetidine for peptic ulcers, clofibrate for {heart problems|congestive heart failure}, the antiinfective dapsone, the immune modulator and antiviral Isoprinosine, the antiinfectives, pentamidine, dapsone, pyrimethamine, co-trimoxazole, amphotericin and flucytosine, vincristine, vinblastine and doxorubicin for cancer treatment, the {defense|immune system|resistant} modulator interferon
What medications connect to Duovir?

{A number of|Many|A lot of} medications connect to Duovir and should either not be taken while you are taking Duovir or only after discussion and instruction from {your physician|your medical professional|a medical expert}:
{Medicines|Medications|Prescription drugs} that cause a serious reaction with Duovir: the antiinfectives, pentamidine, dapsone, pyrimethamine, co-trimoxazole, amphotericin and flucytosine, the antiviral ganciclovir,, vincristine, vinblastine and doxorubicin for cancer treatment, the {defense|immune system|proof} modulator interferon
Drugs that affect Duovir: the antiseptic trimethoprim, the antiinfective atovaquone, probenecid for gout, the antiviral ribavirin, the antiseptic rifampicin, the narcotic {pain reducers|pain killers} codeine and morphine, methadone for treatment of narcotic withdrawal, the non-steroidal antiinflammatoires (NSAID) aspirin, indomethacin, ketoprofen and naproxen, oxazepam and lorazepam for anxiety and sleeping problems, cimetidine for peptic ulcers, clofibrate for {heart problems|congestive heart failure}, the antiinfective dapsone, the immune modulator and antiviral isoprinosine
Drugs that are {afflicted|damaged} by Duovir: the antriretrovirals zalicitabine and stavudine, the anticonvulsant phenytoin
How should Duovir be taken?

You must take your Duovir tablets, {you|one particular} tablet twice daily, with a glass of {drinking water|normal water} and with or without food. Your dose may be adjusted by your doctor, depending on your condition and you should take your Duovir tablets continually for as long as recommended {from your|because of your} doctor.
How long should you take Duovir?

You should take your Duovir tablets continually for as long as recommended by your doctor.
Missed dose of Duovir

If you {pass up|neglect} a dose of Duovir take it as soon as you remember, {unless of course|except if|until} you need to take the next dose, then skip the missed {serving|amount|measure}. Do not take a double dose.
How should Duovir be stored?

You keep your Duovir tablets in their blister {packages|bags|features} until use and store your below 30? C in a cool {dried out|dry out|dried} place.